Categories: C=O Bond Formation > Synthesis of aldehydes >
Synthesis of aldehydes by oxidation of alkenes
Name Reactions
Recent Literature

Osmium tetroxide has been microencapsulated in a polyurea matrix. These
microcapsules have been effectively used as recyclable catalysts in the
dihydroxylation and the oxidative cleavage of olefins.
S. V. Ley, C. Ramarao, A.-L. Lee, N. Ostergaard, S. C. Smith, I. M. Shirley,
Org. Lett., 2003, 5, 185-187.

A gold(I)-catalyzed oxidative cleavage of alkenes with tert-butyl
hydrogenperoxide (TBHP) as the oxidant in the presence of neocuproine
afforded ketones or aldehydes as products.
D. Xing, B. Guan, G. Cai, Z. Fang, L. Yang, Z. Shi, Org. Lett.,
2006, 8, 693-696.

Specific oxidation protocols have been developed for the cleavage of styrenes,
aliphatic olefins, and terminal aliphatic olefins to carbonyl compounds with
ruthenium trichloride as catalyst. Olefins that are not fully substituted are
converted to aldehydes rather than carboxylic acids.
D. Yang, C. Zhang, J. Org. Chem., 2001, 66, 4814-4818.

