Categories: C=O Bond Formation >
Synthesis of esters
Name Reactions
Recent Literature
An efficient oxidation of various acetals, including open-chain acetals,
1,3-dioxanes and 1,3-dioxalanes, with molecular oxygen in the presence of
catalytic amounts of N-hydroxyphthalimide (NHPI) and Co(OAc)2
as co-catalyst gave esters.
B. Karimi, J. Rajabi, Synthesis, 2003, 2373-2377.
An efficient oxidation of cyclic acetals provided hydroxy alkyl esters in good
yields in the presence of MCPBA.
J. Y. Kim, H. Rhee, M. Kim, J. Korean Chem. Soc., 2002, 46,
479-483.
N-Heterocyclic carbenes catalyze the oxidation of various allylic, propargylic,
and benzylic alcohols to esters with manganese(IV) oxide in excellent yields.
Saturated esters can also be accessed from aldehydes using this method. A
desymmetration of meso-1,2-diols using a chiral catalyst is described.
B. E. Maki, A. Chan, E. M. Phillips, K. A. Scheidt, Org. Lett., 2007,
9, 371-374.
