Categories: C=S Bond Formation >
Synthesis of thioketones
Name Reactions
Recent Literature
An expeditious, solvent-free, and high yield conversion of ketones, flavones,
isoflavones, lactones, amides, and esters to the corresponding thio
analogues is described utilizing Lawesson's reagent in a process that
circumvents the use of dry solvents and excess of the reagent.
R. S. Varma, D. Kumar, Org. Lett., 1999, 1, 697-700.
A novel, simple and convenient thionation protocol for carbonyl compounds with
the system PSCl3/H2O/Et3N allows a clean,
rapid, and efficient synthesis of a variety of thiocarbonyl compounds such as
thioamides, thiolactams, thioketones, thioxanthones and thioacridone under
solventless condition with microwave irradiation.
U. Pathak, L. K. Pandey, R. Tank, J. Org. Chem., 2008,
73, 2890-2893.