Categories: N-H Bond Formation >
Deoxygenation of aza-aromatics
Recent Literature
A convenient and chemoselective method for deoxygenation of pyridine N-oxide
derivatives by transfer oxidation of triethylamine under microwave irradiation
is catalysed by [Pd(OAc)2]/dppf.
J. A. Fuentes, M. L. Clarke, Synlett, 2008,
2579-2582.
Sulfoxides and aza-aromatic N-oxides were deoxygenated using a system
of indium and pivaloyl chloride at room temperature to give the
corresponding sulfides and aza-aromatics in high yields.
E. S. Park, S. Hwan, Lee, J. H. Lee, H. J. Rhee, C. M. Yoon, Synthesis, 2005, 3499-3501.
A mild and efficient general method for the deoxygenation of organic N-oxides
such as azoxybenzenes, N-arylnitrones, and N-heteroarene N-oxides
uses the environmentally friendly Lewis acids Zn(OTf)2 and
Cu(OTf)2.
A. Saini, S. Kumar, J. S. Sandhu, Synlett,
2006, 395-398.
