Categories: N-H Bond Formation >
Hydrolysis of imines and related compounds
Recent Literature
A Pd-catalyzed O-arylation of ethyl
acetohydroximate as an hydroxylamine equivalent with aryl chlorides,
bromides, and iodides offers short reaction times and broad substrate scope. The
reaction allows
access to O-arylhydroxylamines that would be difficult to prepare.
Moreover, the O-arylated products can be directly transformed into
substituted benzofurans in a single operation.
T. J. Maimone, S. L. Buchwald, J. Am. Chem. Soc., 2010,
132, 9990-9991.