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Hydrolysis of imines and related compounds

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A Pd-catalyzed O-arylation of ethyl acetohydroximate as an hydroxylamine equivalent with aryl chlorides, bromides, and iodides offers short reaction times and broad substrate scope. The reaction allows access to O-arylhydroxylamines that would be difficult to prepare. Moreover, the O-arylated products can be directly transformed into substituted benzofurans in a single operation.
T. J. Maimone, S. L. Buchwald, J. Am. Chem. Soc., 2010, 132, 9990-9991.