Categories: N-H Bond Formation >
Hydrolysis of imines and related compounds
Recent Literature
An efficient Pd catalyst allows the O-arylation of ethyl acetohydroximate
as an efficient hydroxylamine equivalent with aryl chlorides, bromides, and
iodides. Short reaction times and broad substrate scope allow access to O-arylhydroxylamines
that would be difficult to prepare. Moreover, the O-arylated products so formed
can be directly transformed into substituted benzofurans in a single operation.
T. J. Maimone, S. L. Buchwald, J. Am. Chem. Soc., 2010,
132, 9990-9991.
