Categories: N-H Bond Formation >
Reduction of hydroxamates (Weinreb amides)
Recent Literature

Neutral organic super-electron donors can be used as reducing agents for the
cleavage of N-O bonds in Weinreb amides. This methodology proved to be
applicable to a large array of substrates to afford their reduced counterparts
in good yields.
S. P. Y. Cutulic, J. A. Murphy, H. Farwaha, S.-Z. Zhou, E. Chrystal, Synlett, 2008,
2132-2136.
