Categories: N-O Bond Formation >
Synthesis of nitrones
Recent Literature

A general, high yielding, and user and environmentally friendly catalytic
oxidation procedure for the chemoselective oxidation of imines to nitrones is
reported.
G. Soldaini, F. Cardona, A. Goti, Org. Lett., 2007,
9, 473-476.

Oxidations of organic substrates such as sulfides, secondary amines, N-hydroxylamines,
and tertiary amines with molecular oxygen in the presence of
5-ethyl-3-methyllumiflavinium perchlorate catalyst and hydrazine monohydrate
in 2,2,2-trifluoroethanol occur highly efficiently to give the corresponding
oxidized compounds in excellent yields.
Y. Imada, H. Iida, S. Ono, S.-I. Murahashi, J. Am. Chem. Soc., 2003, 125, 2868-2869.
