Organic Chemistry Portal >
Reactions > Organic Synthesis Search

O-H Bond Formation

Reactions


Reduction of carbonyl compounds


Reduction of carboxyl compounds to alcohols


Reduction of α,β-unsaturated compounds


Reduction of epoxides


Cleavage of ethers


Cleavage of esters


Cleavage of carbonates


Cleavage of carbamates


Cleavage of silyl ethers


Cleavage of acetals


Cleavage of hemiaminals


Recent Literature


Magnesium in methanol is an effective reagent for the chemoselective reduction of ozonides and other peroxides. Mg/MeOH is significantly more reactive than Me2S or PPh3 and somewhat more reactive than Zn/HOAc.
P. Dai, P. H. Dussault, T. K. Trullinger, J. Org. Chem., 2004, 69, 2851-2852.