Categories: Synthesis of N-Heterocycles >
Synthesis of 2-isoxazolines
Recent Literature
3-alkylpropargyl or 3-arylpropargyl hydroxylamines hydrochlorides were
converted to 2-isoxazolines in good yields in refluxing methanol in the presence
of K2CO3. Methods for 3-unsubstituted compounds and the
direct transformation of a O-propargyl phthalimide into 2-isoxazolines
have been developed.
L. Pennicott, S. Lindell, Synlett,
2006, 463-465.
