Categories: Synthesis of N-Heterocycles >
Synthesis of carbazoles
Name Reactions
Recent Literature
A palladium-catalyzed tandem directed C-H
functionalization and amide arylation gave a series of substituted carbazoles. The Pd(0) species
generated are reoxidized to Pd(II) in the presence of Cu(OAc)2 and an atmosphere
of oxygen.
W. C. P. Tsang, N. Zheng, S. L. Buchwald, J. Am. Chem. Soc.,
2005, 127, 14560-14561.
An efficient route to carbazoles and dibenzofurans has
been developed. The reaction of
o-iodoanilines or o-iodophenols with silylaryl triflates in the
presence of CsF to afford N- or O-arylated products is followed by
a cyclization using a Pd catalyst to carbazoles and dibenzofurans in good to
excellent yields. Various functional groups are tolerated.
Z. Liu, R. C. Larock, Org. Lett., 2004, 6, 3739-3741.
