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Synthesis of oxindoles

Recent Literature

A highly regioselective palladium-catalyzed cyclization converts α-chloroacetanilides to oxindoles in good to excellent yields with high functional group compatibility using 2-(di-tert-butylphosphino)biphenyl as ligand and triethylamine as a stoichiometric base.
E. J. Hennessy, S. L. Buchwald, J. Am. Chem. Soc., 2003, 125, 12084-12085.

A small library of α,β-unsaturated oxindoles was prepared by an efficient microwave-assisted one-pot sequence comprising an aromatic substitution followed by an ionic Horner-Wadsworth-Emmons olefination.
A. Teichert, K. Jantos, K. Harms, A. Studer, Org. Lett., 2004, 6, 3477-3480.