Synthesis of sultams and related compounds
Highly strained β-sultams, sulfonyl analogues of β-lactams, were prepared enantio- and diastereoselectively by tertiary amine catalyzed [2 + 2] cycloaddition reactions. β-Sultams are practical precursors of highly enantioenriched β-aminosulfonyl derivatives of biological interest.
M. Zajac, R. Peters, Org. Lett., 2007, 9, 2007-2010.