Organic Chemistry Portal

The Organic Chemistry Portal offers an overview of recent topics, interesting reactions, and information on important chemicals for organic chemists.

Presentations

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The E-Series system from Vapourtec was developed with three main design goals: Ease of use, Robustness, Affordability.

Synthesis, purification and NMR identification of metabolites and API impurities

Archive: 2025, 2024, 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, More

C-O Ring Construction: Boscartin H (Sugita), Hypocretenolide (Ding/Wang/Chen), Oxacyclododecindione (Opatz), Merrillianin (Shiina/Murata), Incargranine A (Dixon), Berkelic Acid (Yoshida)
20 January 2025 - Douglass F. Taber

C-O Ring Construction: The Yu/Qin Synthesis of Nimbolide
13 January 2025 - Douglass F. Taber

The Yang Synthesis of Principinol B
06 January 2025 - Douglass F. Taber

Other Methods for Carbocyclic Construction: Dipiperamide A (Yoon), Acanthodoral (Kalesse), Dysidavarone A (Chong/Lu), Providencin (Roche/West), Vinigrol(Luo), Cochlearol B (Zhao)
30 December 2024 - Douglass F. Taber

Diels-Alder Cycloaddition: Ilicicolin H (Tang/Li), Lucidumone (Li), Venenatine (Zu), Chuanxiongolide L1 (Li/Zheng), Verrubenzospirolactone (Dethe), Pedrolide (Li)
23 December 2024 - Douglass F. Taber

Organic Reactions

Find the most important name reactions in organic chemistry, stability data for the most frequently used protective groups, protection and deprotection methods; browse synthetic transformations.

Abstracts

Abstracts of articles in the field of organic synthesis, published in the most highly regarded organic chemistry journals

Chemicals

A searchable index of more than 1 million chemicals from suppliers worldwide, basic information on widely-used chemical reagents in organic synthesis such as oxidizing and reducing agents.

Chemistry Tools

Molecular Properties Estimation - The OSIRIS Property Explorer lets you draw chemical structures and calculates various drug-relevant properties

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Organic Chemistry - A Definition

Organic chemistry focuses on molecules mainly composed of carbon and hydrogen, along with a handful of other elements - such as oxygen, nitrogen, silicon, sulfur, and phosphorus. Organic chemistry deals with synthetic methods, reaction mechanisms and kinetics, and uses analytical methods for reaction control and purification such as chromatography (TLC, GC, HPLC), and structure confirmation such as NMR and IR, but also structure determination such as NMR and X-ray crystallography. New fields of organic chemistry for example include organometallic chemistry, which is the study of carbon-based compounds that contain metals, and bioorganic chemistry, which combines organic chemistry and biochemistry. Methods of organic chemistry are used in medicinal chemistry, natural product chemistry, and materials science. In the industry, organic chemists work in discovery chemistry (making new molecules) and process optimization (finding better synthetic methods for large scale production).