Organic Chemistry Portal

The Organic Chemistry Portal offers an overview of recent topics, interesting reactions, and information on important chemicals for organic chemists.

Organic Chemistry Highlights

Archive: 2022, 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, More

C-O Ring Construction: Triciadolide C (Wang), Nesteretal A (Ito), Toxicodenane (Han), Dehydro-exo-Brevicomin (Kanomata), Diocollettines A (Houk/Smith), Heliannuol K (Green)
16 May 2022 - Douglass F. Taber

C-O Ring Construction: The Ito Synthesis of Callilongisin B
09 May 2022 - Douglass F. Taber

The Dong Synthesis of Phainanoid A
02 May 2022 - Douglass F. Taber

C-H Functionalization: The Davies/Sorensen Synthesis of Aflatoxin B2
25 April 2022 - Douglass F. Taber

Alkaloid Synthesis: Impatien A (Watson), cis-195J (Schneider), Galanthamine (Zhao), Stemoamide (Tang), Lythranidine (Sherburn), Aspidospermine (Liu)
18 April 2022 - Douglass F. Taber

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Organic Reactions

Find the most important name reactions in organic chemistry, stability data for the most frequently used protective groups, protection and deprotection methods; browse synthetic transformations


Abstracts of articles in the field of organic synthesis, published in the most highly regarded organic chemistry journals


A searchable index of more than 1 million chemicals from suppliers worldwide, basic information on widely-used chemical reagents in organic synthesis such as oxidizing and reducing agents.

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Top Picks for Organic Chemistry Students:
Organic Chemistry - Clayden Medicinal Chemistry - Patrick Advanced Organic Chemistry - Carey, Sundberg


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Organic Chemistry - A Definition

Organic chemistry focuses on molecules mainly composed of carbon and hydrogen, along with a handful of other elements - such as oxygen, nitrogen, silicon, sulfur, and phosphorus. Organic chemistry deals with synthetic methods, reaction mechanisms and kinetics, and uses analytical methods for reaction control and purification such as chromatography (TLC, GC, HPLC), and structure confirmation such as NMR and IR, but also structure determination such as NMR and X-ray crystallography. New fields of organic chemistry for example include organometallic chemistry, which is the study of carbon-based compounds that contain metals, and bioorganic chemistry, which combines organic chemistry and biochemistry. Methods of organic chemistry are used in medicinal chemistry, natural product chemistry, and materials science. In the industry, organic chemists work in discovery chemistry (making new molecules) and process optimization (finding better synthetic methods for large scale production).