Organic Chemistry Portal



New Abstracts

Abstracts of articles in the field of organic synthesis,
published in the most highly regarded organic chemistry journals


Between March, 8th and April, 4th, we publish additional daily updates on weekdays. This page will be updated 40% more often and will feature bonus information only available for 24 h. It's therefore recommended that you check the information on a daily basis in the upcoming weeks.

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Nucleophilic Organic Base DABCO-Mediated Chemospecific Meinwald Rearrangement of Terminal Epoxides into Methyl Ketones
S. Li, Y. Shi, P. Li, J. Xu, J. Org. Chem., 2019, 84, 4443-4450.

N-Heterocyclic Olefin Catalyzed Silylation and Hydrosilylation Reactions of Hydroxyl and Carbonyl Compounds
U. Kaya, U. P. N. Tran, D. Enders, J. Ho, T. V. Nguyen, Org. Lett., 2017, 19, 1398-1401.

The Synthesis of Medium-Chain-Length β-Hydroxy Esters via the Reformatsky Reaction
M. Sailer, K. I. Dumichi, J. L. Sorensen, Synthesis, 2015, 47, 79-82.

Nickel-Catalyzed Carboxylation of Aryl and Heteroaryl Fluorosulfates Using Carbon Dioxide
C. Ma, C.-Q. Zhao, X.-T. Xu, Z.-M. Li, X.-Y. Wang, K. Zhang, T.-S. Mei, Org. Lett., 2019, 21, 2464-2467.

Efficient Ruthenium(II)-Catalyzed Direct Reductive Amination of Aldehydes under Mild Conditions Using Hydrosilane as the Reductant
B. Li, J. Zheng, W. Zeng, Y. Li, L. Chen, Synthesis, 2017, 49, 1349-1355.

Synthesis of Terminal Allenes through Copper-Mediated Cross-Coupling of Ethyne with N-Tosylhydrazones or α-Diazoesters
F. Ye, C. Wang, X. Ma, M. L. Hossain, Y. Xia, Y. Zhang, J. Wang, J. Org. Chem., 2015, 80, 647-652.

Direct Transformation of Aryl 2-Pyridyl Esters to Secondary Benzylic Alcohols by Nickel Relay Catalysis
X. Wu, X. Li, W. Huang, W. Wang, H. Xu, L. Cai, J. Qu, Y. Chen, Org. Lett., 2019, 21, 2453-2458.

Iron-Catalyzed Synthesis of 2H-Imidazoles from Oxime Acetates and Vinyl Azides under Redox-Neutral Conditions
Z. Zhu, X. Tang, J. Li, X. Li, W. Wu, G. Deng, H. Jiang, Org. Lett., 2017, 19, 1370-1373.

Practical Route to 2-Quinolinones via a Pd-Catalyzed C-H Bond Activation/C-C Bond Formation/Cyclization Cascade Reaction
J. Wu, S. Xiang, J. Zeng, M. Leow, X.-W. Liu, Org. Lett., 2015, 17, 222-225.

Chiral Cyclopentadienyl Cobalt(III) Complexes Enable Highly Enantioselective 3d-Metal-Catalyzed C-H Functionalizations
K. Ozols, Y.-S. Jang, N. Cramer, J. Am. Chem. Soc., 2019, 141, 5675-5680.

Selective Oxidation of Styrene Derivatives to Ketones over Palladium(0)/Carbon with Hydrogen Peroxide as the Sole Oxidant
X. Xia, X. Gao, J. Xu, C. Hu, X. Peng, Synlett, 2017, 28, 607-610.

Mild Palladium-Catalyzed Cyanation of (Hetero)aryl Halides and Triflates in Aqueous Media
D. T. Cohen, S. L. Buchwald, Org. Lett., 2015, 17, 202-205.

KOAc-Catalyzed One-Pot Three-Component 1,3-Dipolar Cycloaddition of α-Diazo Compounds, Nitrosoarenes, and Alkenes: An Approach to Functionalized Isoxazolidines
X. Li, T. Feng, D. Li, H. Chang, W. Gao, W. Wei, J. Org. Chem., 2019, 84, 4402-4412.

Assembly of Diversely Substituted Quinolines via Aerobic Oxidative Aromatization from Simple Alcohols and Anilines
J. Li, J. Zhang, H. Yang, G. Jiang, J. Org. Chem., 2017, 82, 3245-3251.

Synthesis of α-Methylene-β-Lactams via PPh3-Catalyzed Umpolung Cyclization of Propiolamides
L. Zhu, Y. Xiong, C. Li, J. Org. Chem., 2015, 80, 628-633.

Molybdenum-Catalyzed Diastereoselective anti-Dihydroxylation of Secondary Allylic Alcohols
P. Song, P. Yu, J.-S. Lin, Y. Li, N.-Y. Yang, X.-Y. Liu, Org. Lett., 2017, 19, 1330-1333.

Transition-Metal-Free β-C-H Bond Carbonylation of Enamides or Amides with a Trifluoromethyl Group as CO Surrogate for the Synthesis of 1,3-Oxazin-6-ones
P. Song, P. Yu, J.-S. Lin, Y. Li, N.-Y. Yang, X.-Y. Liu, Org. Lett., 2017, 19, 1330-1333.

Propargylation of Aldehydes Using Potassium Allenyltrifluoroborate
T. R. Couto, J. J. R. Freitas, J. C. R. Freitas, I. H. Cavelcanti, P. H. Menezes, R. A. Oliveira, Synthesis, 2015, 47, 71-78.

Allyl-Nickel Catalysis Enables Carbonyl Dehydrogenation and Oxidative Cycloalkenylation of Ketones
D. Huang, S. M. Szewczyk, P. Zhang, T. R. Newhouse, J. Am. Chem. Soc., 2019, 141, 5669-5674.

Synthesis of Complex Tertiary Glycolates by Enantioconvergent Arylation of Stereochemically Labile α-Keto Esters
S. L. Bartlett, K. M. Keiter, J. S. Johnson, J. Am. Chem. Soc., 2017, 139, 3911-3916.

Supported Gold Nanoparticle-Catalyzed Hydration of Alkynes under Basic Conditions
S. Liang, J. Jasinski, G. B. Hammond, B. Xu, Org. Lett., 2015, 17, 162-165.

Photoredox Radical/Polar Crossover Enables Construction of Saturated Nitrogen Heterocycles
L. R. E. Pantaine, J. A. Milligan, J. K. Matsui, C. B. Kelly, G. A. Molander, Org. Lett., 2019, 21, 2317-2321.

The Conversion of tert-Butyl Esters to Acid Chlorides Using Thionyl Chloride
J. A. Greenberg, T. Sammakia, J. Org. Chem., 2017, 82, 3245-3251.

Application of Bidentate Oxazoline-Carbene Ligands with Planar and Central Chirality in Asymmetric β-Boration of α,β-Unsaturated Esters
Z. Niu, J. Chen, Z. Chen, M. Ma, C. Song, Y. Ma, J. Org. Chem., 2015, 80, 602-608.

Asymmetric Synthesis of γ-Hydroxy Pinacolboronates through Copper-Catalyzed Enantioselective Hydroboration of α,β-Unsaturated Aldehydes
W. J. Jang, S. M. Song, Y. Park, J. Yun, J. Org. Chem., 2019, 84, 4429-4434.

Cobalt-Catalyzed 1,1-Diboration of Terminal Alkynes: Scope, Mechanism, and Synthetic Applications
S. Krautwald, M. J. Bezdek, P. J. Chirik, J. Am. Chem. Soc., 2017, 139, 3868-3875.

Copper-Catalyzed Three-Component Synthesis of Benzothiazolethiones from o-Iodoanilines, Isocyanide, and Potassium Sulfide
P. Dang, W. Zeng, Y. Liang, Org. Lett., 2015, 17, 34-37.

Dearomatization-Rearomatization Strategy for Reductive Cross-Coupling of Indoles with Ketones in Water
Z. Wang, H. Zeng, C.-J. Li, Org. Lett., 2019, 21, 2302-2306.

Cross-Dehydrogenative C-H Amination of Indoles under Aerobic Photo-oxidative Conditions
T. Yamaguchi, E. Yamaguchi, A. Itoh, Org. Lett., 2017, 19, 1282-1285.

Mild and Selective Deprotection of tert-Butyl(dimethyl)silyl Ethers with Catalytic­ Amounts of Sodium Tetrachloroaurate(III) Dihydrate
Q. Zhang, X. Kang, L. Long, L. Zhu, Y. Chai, Synthesis, 2015, 47, 55-64.