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Silane-Promoted Cycloisomerization of Functionalized 1,6-Dienes Catalyzed by a Cationic (π-Allyl)palladium Complex

Ross A. Widenhoefer and Nicholas S. Perch

*Duke University, P. M. Gross Chemical Laboratory, Durham, North Carolina 27708-0346, Email:

R. A. Widenhoefer, N. S. Perch, Org. Lett., 1999, 1, 1103-1105.

DOI: 10.1021/ol9908981

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A 1:1 mixture of the (π-allyl)palladium complex (η3-C3H5)Pd(Cl)PCy3 and NaB[3,5-C6H3(CF3)2]4 catalyzed the cycloisomerization of functionalized 1,6-dienes in the presence of HSiEt3 to provide 1,2-disubstituted cyclopentenes in good yield.

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Cycloisomerization of Functionalized 1,5- and 1,6-Dienes Catalyzed by Cationic Palladium Phenanthroline Complexes

P. Kisanga, L. A. Goj, R. A. Widenhoefer, J. Org. Chem., 2001, 66, 635-637.

Key Words

cyclopentenes, triethylsilane

ID: J54-Y1999