Convenient Catalytic Free Radical Reductions of Alkyl Halides Using an Organotin Reagent on Non-Cross-Linked Polystyrene Support
Eric J. Enholm and James P. Schulte
*Department of Chemistry, University of Florida, Gainesville, Florida 32611,
Email: enholm
chem.ufl.edu
E. J. Enholm, J. P. Schulte, Org. Lett., 1999, 1, 1275-1277.
DOI: 10.1021/ol990945p
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Abstract
A highly efficient and catalytic organotin reagent on soluble support has been developed for free radical reactions. A variety of alkyl halides (1°, 2°, 3°, aryl) underwent radical reductions in good isolated yields using only 0.01-0.2 equiv of the polymer catalyst.
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Key Words
dehalogenations, organotin hydrides, sodium borohydride
ID: J54-Y1999
