Efficient Radical Oxygenation of α-Iodocarboxylic Acid Derivatives
Nobuhiro Kihara, Cyril Ollivier and Philippe Renaud*
*Université de Fribourg, Institut de Chimie Organique, Pérolles, CH-1700 Fribourg, Switzerland,
Email: philippe.renaud
dcb.unibe.ch
N. Kihara, C. Ollivier, P. Renaud, Org. Lett., 1999, 1, 1419-1422.
DOI: 10.1021/ol990971n
Abstract
Treatment of α-iodocarboxylic acid derivatives with 2 equiv of triethylborane under oxygen atmosphere gives the corresponding α-hydroxy acid derivatives. Tertiary iodides and substrates sensitive to nucleophiles are efficiently converted to alcohols.
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Key Words
ID: J54-Y1999
