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Palladium-Catalyzed Arylation of α-Methylene-γ-butyrolactone: 3-Benzylfuran-2(5H)-ones vs (Z)-Benzylidene-γ-butyrolactones and Their Reduction to 3-Benzyl-γ-butyrolactones

Antonio Arcadi*, Marco Chiarini, Fabio Marinelli, Zoltán Berente, and Lāszlō Kollār

*Dipartimento di Chimica, Ingegneria Chimica e Materiali, Via Vetoio, 67010 Coppito Due (AQ) Italy, Email:

A. Arcadi, M. Chiarini, F. Marinelli, Z. Berente, L. Kollār, Org. Lett., 2000, 2, 69-72.

DOI: 10.1021/ol9912130

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A combined palladium-catalyzed arylation/hydrogenation of α-methylene-γ-butyrolactones provides functionalized α-benzyl-γ-butyrolactones in good yields.

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Key Words

butyrolactones, hydrogen

ID: J54-Y2000