Concerted Catalytic Reactions for Conversion of Ketones or Enol Acetates to Chiral Acetates
Hyun M. Jung, Jeong H. Koh, Mahn-Joo Kim and Jaiwook Park*
*Department of Chemistry and Division of Molecular & Life Science, Pohang University of Science and Technology (POSTECH), San 31 Hyoja Dong, Pohang 790-784, Korea, Email: pjwpostech.ac.kr
H. M. Jung, J. H. Koh, M.-J. Kim, J. Park, Org. Lett., 2000, 2, 397-399.
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The combination of lipase and a ruthenium complex catalyzes the asymmetric transformation of enol acetates or ketones to chiral acetates in high yields with high optical purities in the presence of 2,6-dimethylheptan-4-ol as a hydrogen donor and 4-chlorophenyl acetate as an acyl donor.
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Practical Ruthenium/Lipase-Catalyzed Asymmetric Transformations of Ketones and Enol Acetates to Chiral Acetates
H. M. Jung, J. H. Koh, M.-J. Kim, J. Park, Org. Lett., 2000, 2, 2487-2490.
reduction of carbonyl compounds, asymmetric acylation