Palladium-Catalyzed Cyanation of Propargylic Carbonates with Trimethylsilyl Cyanide
Yasushi Tsuji, Masahiko Taniguchi, Tamami Yasuda, Takashi Kawamura and Yasushi Obora
*Catalysis Research Center and Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0811, Japan
Y. Tsuji, M. Taniguchi, T. Yasuda, T. Kawamura, Y. Obora, Org. Lett., 2000, 2, 2635-2637.
DOI: 10.1021/ol006160x
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Abstract
Pd(PPh3)4 catalyzes a cyanation of propargylic carbonates with trimethylsilyl cyanide in THF under reflux to afford cyanoallenes. The use of trimethylsilyl cyanide in excess (6 equiv) provides dicyanated products in high yields.
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Key Words
ID: J54-Y2000
