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Organometallic Reactions in Aqueous Media. Indium-Mediated 1,3-Butadien-2-ylation of Carbonyl Compounds

Wenshuo Lu, Jihai Ma, Yang Yang and Tak Hang Chan*

*Department of Chemistry, McGill University, Montreal, Quebec, Canada, H3A 2K6

W. Lu, J. Ma, Y. Yang, T. H. Chan, Org. Lett., 2000, 2, 3469-3471.

DOI: 10.1021/ol000239k


An indium-mediated coupling of 1,4-dibromo-2-butyne with carbonyl compounds in aqueous media provides 1,3-butadien-2-ylmethanols in good yields.

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Key Words

allylic alcohols, 1,3-dienes

ID: J54-Y2000