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Ruthenium Complex-Catalyzed anti-Markovnikov Hydration of Terminal Alkynes

Toshiaki Suzuki, Makoto Tokunaga and Yasuo Wakatsuki*

*RIKEN (The Institute of Physical and Chemical Research) and PRESTO (Japan Science and Technology Corporation), Wako-shi, Saitama 351-0198, Japan

T. Sukuzi, M. Tokunaga, Y. Wakatsuki, Org. Lett., 2001, 3, 119-122.

DOI: 10.1021/ol0003937


A highly regioselective, efficient, and substituent-tolerant anti-Markovnikov hydration of terminal alkynes provides n-aldehydes in the presence of a catalytic amount of RuCpCl(dppm).

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Key Words

anti-Markovnikov Hydration of Terminal Alkynes

ID: J54-Y2001