A Convenient Method for the Efficient Removal of Ruthenium Byproducts Generated during Olefin Metathesis Reactions
Yu Mi Ahn, KyoungLang Yang and Gunda I. Georg*
*Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66044,
Email: georg
umn.edu
Y. M. Ahn, K. Yang, G. I. Georg, Org. Lett., 2001, 3, 1411-1413.
DOI: 10.1021/ol010045k
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Abstract
Treatment of the crude reaction products with triphenylphosphine oxide or dimethyl sulfoxide, followed by filtration through silica gel enables an efficient and practical removal of ruthenium byproducts generated during olefin metathesis reactions with Grubbs catalysts.
Key Words
ring closing metathesis, olefin metathesis
ID: J54-Y2001
