3-Aryl-2-oxazolidinones through the Palladium-Catalyzed N-Arylation of 2-Oxazolidinones
Sandro Cacchi*, Giancarlo Fabrizi, Antonella Goggiamani and Giovanni Zappia
*Dipartimento di Studi di Chimica e Tecnologia delle Sostanza Biologicamente Attive, Università degli Studi
"La Sapienza", P.le A. Moro 5, 00185 Rome, Italy,
Email: Sandro.Cacchi
uniroma1.it
S. Cacchi, G. Fabrizi, A. Goggiamani, G. Zappia, Org. Lett., 2001, 3, 2539-2541.
DOI: 10.1021/ol016208m
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Abstract
A palladium-catalyzed N-arylation of 2-oxazolidinones with aryl bromides provides 3-aryl-2-oxazolidinones in good yields. The nature of aryl bromides, phosphine ligands, bases, and solvents strongly affects the reaction outcome.
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Key Words
ID: J54-Y2001
