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Chloroprene as a Source of Fine Chemicals:  Palladium-Catalyzed Synthesis of Terminal Allenes

Masamichi Ogasawara, Hisashi Ikeda, Takashi Nagano and Tamio Hayashi

*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan

M. Ogasawara, H. Ikeda, T. Nagano, T. Hayashi, Org. Lett., 2001, 3, 2615-2617.

DOI: 10.1021/ol016320k

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A palladium-catalyzed reaction of chloroprene (2-chloro-1,3-butadiene) with soft nucleophiles provides several functionalized terminal allenes in good yield.

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Key Words

allenes, active methylene compounds, Tsuji-Trost Reaction

ID: J54-Y2001