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A Simple, Efficient, and General Method for the Conversion of Alcohols into Alkyl Iodides by a CeCl37H2O/NaI System in Acetonitrile

Milena Di Deo, Enrico Marcantoni*, Elisabetta Torregiani, Giuseppe Bartoli*, Maria Cristina Bellucci, Marcella Bosco and Letizia Sambri

*Dipartimento di Scienze Chimiche, via S. Agostino 1, I-62032 Camerino (MC); Dipartimento di Chimica Organica "A. Mangini", v.le Risorgimento 4, I-40136 Bologna, Italy

M. Di Deo, E. Marcantoni, E. Torregiani, G. Bartoli, M. C. Bellucci, M. Bosco, L. Sambri, J. Org. Chem., 2000, 65, 2830-2833.

DOI: 10.1021/jo991894c

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The use of a CeCl37H2O/NaI system in acetonitrile enables an exceedingly mild preparation of iodides from alcohols. The simplicity of this approach, the low cost of reagents, and the ease of use display the attractiveness of the present method for a wide variety of alcohols.

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Key Words

alkyl iodides, benzyl iodides, allyl iodides

ID: J42-Y2000