Preparation of 1,5-Disubstituted Pyrrolidin-2-ones
Alan R. Katritzky*, Shamal Mehta, Hai-Ying He and Xilin Cui
*Center for Heterocyclic Chemistry, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200
A. R. Katritzky, S. Mehta, H.-Y. He, X. Cui, J. Org. Chem., 2000, 65, 4364-4369.
DOI: 10.1021/jo000219w
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Abstract
1,5-Disubstituted pyrrolidin-2-ones were synthesized in good yields via the nucleophilic substitution of 5-(benzotriazol-1-yl)-1-substituted-pyrrolidin-2-ones with allylsilanes, organozinc reagents, and phosphorus compounds.
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Key Words
ID: J42-Y2000
