Oxidation of Methyl Trimethylsilyl Ketene Acetals to α-Hydroxyesters with Urea Hydrogen Peroxide Catalyzed by Methyltrioxorhenium
Saša Stanković and James H. Espenson*
*Ames Laboratory and Department of Chemistry, Iowa State University, Ames, Iowa 50011
S. Stanković, J. H. Espenson, J. Org. Chem., 2000, 65, 5528-5530.
Methyltrioxorhenium (MTO) catalyzes an oxidation of methyl trimethylsilyl ketene acetals with urea hydrogen peroxide to afford α-hydroxy and α-siloxy esters. On treatment with potassium fluoride, the α-hydroxy esters are obtained in high yields.
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