Highly Efficient Selective Monohydrolysis of Symmetric Diesters
Satomi Niwayama*
*Department of Chemistry, Oklahoma State University,
Stillwater, Oklahoma 74078-3071,
Email: niwayama
mmm.muroran-it.ac.jp
S. Niwayama, J. Org. Chem., 2000, 65, 5834-5836.
DOI: 10.1021/jo0001986
Abstract
A highly efficient semi-two-phase reaction using THF-aqueous NaOH at 0°C provides half-esters from symmetric diesters in high yields. Diesters that afforded the corresponding half-esters in quantitative yields all possess two carboalkoxy groups in "cis" or "geminal" orientation.
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Key Words
ID: J42-Y2000
