A novel and convenient method for trifluoromethylation of organic halides using CF3SiR'3/KF/Cu(I) system
Hisao Urata, Takamasa Fuchikami*
*Sagami Chemical Research Center 4-4-1 Nishi-Ohnuma, Sagamihara, Kanagawa 229, Japan
H. Urata, T. Fuchikami, Tetrahedron Lett., 1991, 32, 91-94.
DOI: 10.1016/S0040-4039(00)71226-3
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Abstract
Fluoride ions induce a cross-coupling reaction of organic halides with trifluoromethyltrialkylsilanes in the presence of Cu(I) salts under mild reaction conditions to provide the corresponding trifluoromethylated products in good yields.
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Key Words
trifluoromethyl arenes, trifluoromethyl alkenes
ID: JXX-Y1991
