Preparation of Functionalized Arylmagnesium Reagents Bearing an o-Chloromethyl Group
Thomas Delacroix, Laurent Bérillon, Gérard Cahiez and Paul Knochel*
*Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377 Munich, Germany, Email: paul.knochelcup.uni-muenchen.de
T. Delacroix, L. Bérillon, G. Cahiez, P. Knochel, J. Org. Chem., 2000, 65, 8108-8110.
DOI: 10.1021/jo000971x
see article for more reactions
Abstract
A convenient method enables the preparation of arylmagnesium reagents bearing an ortho-chloromethyl group. These reagents proved to be very useful for preparing various functionalized heterocycles such as isobenzofurans, phthalimidines, and benzoazepines.
see article for more examples
Key Words
ID: J42-Y2000