Organic Chemistry Portal

Abstracts

Search:

Preparation of Functionalized Arylmagnesium Reagents Bearing an o-Chloromethyl Group

Thomas Delacroix, Laurent Bérillon, Gérard Cahiez and Paul Knochel*

*Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377 Munich, Germany, Email: paul.knochelcup.uni-muenchen.de

T. Delacroix, L. Bérillon, G. Cahiez, P. Knochel, J. Org. Chem., 2000, 65, 8108-8110.

DOI: 10.1021/jo000971x


see article for more reactions

Abstract

A convenient method enables the preparation of arylmagnesium reagents bearing an ortho-chloromethyl group. These reagents proved to be very useful for preparing various functionalized heterocycles such as isobenzofurans, phthalimidines, and benzoazepines.

see article for more examples



Key Words

1,3-dihydro-2-benzofurans


ID: J42-Y2000