N-Acylbenzotriazoles: Neutral Acylating Reagents for the Preparation of Primary, Secondary, and Tertiary Amides
Alan R. Katritzky*, Hai-Ying He and Kazuyuki Suzuki
*Center for Heterocyclic Chemistry, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200
A. R. Katritzky, H.-Y. He, K. Suzuki, J. Org. Chem., 2000, 65, 8210-8213.
DOI: 10.1021/jo000792f
see article for more reactions
Abstract
Readily available N-acylbenzotriazoles efficiently acylate aqueous ammonia and primary and secondary amines to give primary, secondary, and tertiary amides in very good yields.
see article for more examples
Efficient Conversion of Carboxylic Acids into N-Acylbenzotriazoles
A. R. Katritzky, N. Kirichenko, B. V. Rogovoy, Synthesis, 2003, 2777-2780.
Efficient Microwave Access to Polysubstituted Amidines from Imidoylbenzotriazoles
A. R. Katritzky, C. Cai, S. K. Singh, J. Org. Chem., 2006, 71, 3375-3380.
Key Words
ID: J42-Y2000
