An Efficient Ketone-Catalyzed Epoxidation Using Hydrogen Peroxide as Oxidant

Lianhe Shu and Yian Shi

*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, Email: yian.shicolostate.edu

L. Shu, Y. Shi, J. Org. Chem., 2000, 65, 8807-8810.

DOI: 10.1021/jo001180y

---

see article for more reactions

Abstract

Trifluoroacetone catalyzes a mild and operationally simple epoxidation of various alkens in good yields using hydrogen peroxide as primary oxidant at high pH. The use of H₂O₂ as oxidant significantly reduces the amount of solvent and salts introduced.

see article for more examples

---

---

Key Words

hydrogen peroxide, epoxides, organocatalysis

---

ID: J42-Y2000