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Reduction and Coupling Reactions of Carbonyl Compounds Using Samarium Metal in Aqueous Media

Sanjay Talukdar and Jim-Min Fang

*Department of Chemistry, National Taiwan University, Taipei, Taiwan 106, Republic of China, Email:

S. Talukdar, J.-M. Fang, J. Org. Chem., 2001, 66, 330-333.

DOI: 10.1021/jo001362s


Sm in aqueous HCl is an environmentally benign reducing agent. Whereas aromatic carbonyls underwent pinacol coupling reactions in an efficient manner in Sm/2 M HCl/THF, unimolecular reductions of aliphatic aldehydes provided alcohols.

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Key Words

pinacol coupling, reduction of carbonyl compounds, samarium (low valent)

ID: J42-Y2001