Application of NAD(P)H Model Hantzsch 1,4-Dihydropyridine as a Mild Reducing Agent in Preparation of Cyclo Compounds
Xiao-Qing Zhu*, Hong-Yi Wang, Jian-Shuang Wang and You-Cheng Liu
*Department of Chemistry, National Key Laboratory of
Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China, Email: xqzhu
nankai.edu.cn
X.-Q. Zhu, H.-Y. Wang, J.-S. Wang, Y.-C. Liu, J. Org. Chem., 2001, 66, 344-347.
DOI: 10.1021/jo001362s
see article for more reactions
Abstract
NAD(P)H mimic reactions with Hantzsch 1,4-dihydropyridine provide three-, five- and seven-membered ring compounds. The method offers readily available starting materials, very high yields, mild conditions, and simple workup.
proposed mechanism
Key Words
ID: J42-Y2001
