Selective Reduction of Terminal Alkynes to Alkenes by Indium Metal
Brindaban C. Ranu*, Jyotirmoy Dutta and Sankar K. Guchhait
*Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Calcutta - 700 032, India, Email: ocbcriacs.res.in
B. C. Ranu, J. Dutta, S. K. Guchhait, J. Org. Chem., 2001, 66, 5413-5418.
The use of indium metal in aqueous ethanol enables a highly selective reduction of aryl propargyl ethers, amines, and esters in high yields. This method avoids over-reduction of the double bond formed and tolerates several easily reducible functionalities.
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Indium, Semireduction of Alkynes