A Versatile New Catalyst for the Enantioselective Isomerization of Allylic Alcohols to Aldehydes: Scope and Mechanistic Studies
Ken Tanaka and Gregory C. Fu*
*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139,
Email: gcfu
caltech.edu
K. Tanaka, G. C. Fu, J. Org. Chem., 2001, 66, 8154-8159.
DOI: 10.1021/jo010792v
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Abstract
A rhodium complex derived from a planar-chiral bidentate phosphaferrocene ligand serves as an effective catalyst for asymmetric isomerizations of allylic alcohols to aldehydes. The method offers improved yields, scope, and enantioselectivities. The catalyst is air-stable and can be recovered at the end of the reaction.
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Key Words
isomerisation of allylic alcohols
ID: J42-Y2001
