Deracemization of Baylis-Hillman Adducts
Barry M. Trost*, Hon-Chung Tsui and F. Dean Toste
*Department of Chemistry, Stanford University Stanford, California 94305
B. M. Trost, H.-C. Tsui, F. D. Toste, J. Am. Chem. Soc., 2000, 122, 3534-3535.
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A dynamic kinetic asymmetric transformation (DYKAT) process constitutes a reasonable alternative strategy to access versatile Baylis-Hillman derivatives in highly enantiomerically enriched form. By using an oxygen nucleophile that can become a hydroxyl group, the process constitutes a deracemization.
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