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Synthesis of Functionalized Olefins by Cross and Ring-Closing Metatheses

Arnab K. Chatterjee, John P. Morgan, Matthias Scholl and Robert H. Grubbs

*Department of Chemistry, Stanford University Stanford, California 94305

A. K. Chatterjee, J. P. Morgan, M. Scholl, R. H. Grubbs, J. Am. Chem. Soc., 2000, 122, 3783-3784.

DOI: 10.1021/ja9939744

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A highly active ruthenium-based olefin metathesis catalyst, which contains a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligand, was found to efficiently catalyze cross-metathesis and ring-closing metathesis of a variety of electron-deficient olefins. The functional group compatibility of the catalyst significantly expands the range of olefins that can participate in the olefin metathesis reaction.

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Key Words

Cross Metathesis, Ring-Closing Metathesis, enones, unsaturated esters

ID: J48-Y2000