Highly Effective Chiral Dipyridylphosphine Ligands: Synthesis, Structural Determination, and Applications in the Ru-Catalyzed Asymmetric Hydrogenation Reactions
Cheng-Chao Pai, Ching-Wen Lin, Chi-Ching Lin, Chih-Chiang Chen, Albert S. C. Chan* and Wing Tak Wong
*Open Laboratory of Chirotechnology and Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Hong Kong,
China, Email: chenxz3
mail.sysu.edu.cn
C.-C. Pai, C.-W. Lin, C.-C. Lin, C.-C. Chen, A. S. C. Chan, W. T. Wong, J. Am. Chem. Soc., 2000, 122, 11513-11514.
DOI: 10.1021/ja000163n
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Abstract
A chiral atropisomeric dipyridylphosphine ligand (P-phos) forms well-defined
ruthenium complexes that offer high enantioselectivities in the catalytic
hydrogenation of 2-(6'-methoxy-2'-naphthyl)propenoic
acid and β-ketoesters.
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Key Words
reduction of carbonyl compounds, hydrogen
ID: J48-Y2000
