Screening of Homogeneous Catalysts by Fluorescence Resonance Energy Transfer. Identification of Catalysts for Room-Temperature Heck Reactions
James P. Stambuli, Shaun R. Stauffer, Kevin H. Shaughnessy and John F. Hartwig*
*Department of Chemistry, Yale University P.O. Box 208107, New Haven, Connecticut 06520-8107
J. P. Sambuli, S. R. Stauffer, K. H. Shaughnessy, J. F. Hartwig, J. Am. Chem. Soc., 2001, 123, 2677-2678.
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A method to screen for transition metal-catalyzed reactions based on Fluorescence Resonance Energy Transfer (FRET) was used to identify catalysts for room-temperature Heck reactions of aryl bromides.
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FRET assay with a reagent containing a fluorophore and a second containing a quencher
D.-H. Lee, A. Taher, S. Hossain, M.-J. Jin, Org. Lett., 2011, 13, 5540-5543.