Palladium-Catalyzed Cross-Coupling Reaction of Alkenyldimethyl(2-pyridyl)silanes with Organic Halides:  Complete Switch from the Carbometalation Pathway to the Transmetalation Pathway

Kenichiro Itami, Toshiki Nokami and Jun-ichi Yoshida*

*Department of Synthetic Chemistry and Biological Chemistry Kyoto University, Yoshida, Kyoto 606-8501, Japan

K. Itami, T. Nokami, J.-i. Yoshida, J. Am. Chem. Soc., 2001, 123, 5600-5601.

DOI: 10.1021/ja015655u

---

see article for more reactions

Abstract

A highly efficient palladium-catalyzed cross-coupling reaction of alkenyldimethyl(2-pyridyl)silanes with organic halides has been developed. The potentially occurring two reaction pathways (carbometalation and transmetalation) were perfectly controlled by simply changing the additives.

see article for more examples

---

---

Key Words

dienylation, alkenylation, Hiyama Coupling

---

ID: J48-Y2001