Dehydration Reactions in Water. Surfactant-Type Brønsted Acid-Catalyzed Direct Esterification of Carboxylic Acids with Alcohols in an Emulsion System
Kei Manabe, Xiang-Min Sun and Shū Kobayashi
*Graduate School of Pharmaceutical Sciences, The University
of Tokyo, CREST, JST, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan,
Email: shu_kobayashi
chem.s.u-tokyo.ac.jp
K. Manabe, X.-M. Sun, S. Kobayashi, J. Am. Chem. Soc., 2001, 123, 10101-10102.
DOI: 10.1021/ja016338q
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Abstract
The use of DBSA (p-dodecylbenzenesulfonic acid) as a surfactant-type Brønsted acid catalyst enables selective esterifications in water. The reactions need neither dehydrating agents nor azeotropic removal of water. Instead, the catalyst and substrates in the present system assemble together through hydrophobic interactions to form devices for dehydration reactions.
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Direct esterification by dehydration in the presence of a surfactant-type catalyst in water
Key Words
esterification, green chemistry
ID: J48-Y2001
