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Carboxylic Acids from Primary Alcohols and Aldehydes by a Pyridinium Chlorochromate Catalyzed Oxidation

Mo Hunsen*

*Department of Chemistry, Kenyon College, Gambier, OH 43022, USA, Email:

M. Hunsen, Synthesis, 2005, 2487-2490.

DOI: 10.1055/s-2005-872085


A facile and quantitative preparation of carboxylic acids by a pyridinium chlorochromate (PCC) catalyzed (2 mol%) oxidation of primary alcohols and aldehydes using 2.2 equivalents and 1.1 equivalents of H5IO6, respectively, in acetonitrile is described here.

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Key Words

alcohols, aldehydes, oxidation, carboxylic acids, catalysis, pyridinium chlorochromate (PCC), periodic acid

ID: J66-Y2005-1640