Organic Chemistry Portal



The Chemistry of Alkylstrontium Halide Analogues, Part 2: Barbier-Type Dialkylation of Esters with Alkyl Halides

Norikazu Miyoshi *, Tsuyoshi Matsuo, Makoto Wada

*Department of Chemistry, Faculty of Integrated Arts and Sciences, The University of Tokushima, 1-1 Minamijosanjima, Tokushima 770-8502, Japan, Email:

N. Miyoshi, T. Matsuo, M. Wada, Eur. J. Org. Chem., 2005, 4253-4255.

DOI: 10.1002/ejoc.200500484


Barbier-type alkylation of esters with alkyl iodides proceeded smoothly at room temperature in the presence of metallic strontium under argon to afford the corresponding dialkylated alcohols in good yields.

see article for more examples

Key Words

Strontium, Alcohols, Barbier-type reaction, Ester

ID: J24-Y2005-1730