Organic Chemistry Portal



Triazole-Based Monophosphines for Suzuki-Miyaura Coupling and Amination Reactions of Aryl Chlorides

Duan Liu, Wenzhong Gao, Qian Dai and Xumu Zhang*

*Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, Email:

D. Liu, W. Gao, Q. Dai, X. Zhang, Org. Lett., 2005, 7, 4907-4910.

DOI: 10.1021/ol051844w

see article for more examples


Triazole-based monophosphine ligands have been prepared via efficient cycloadditions. Palladium complexes derived from these ligands are highly active catalysts for Suzuki-Miyaura coupling and amination reactions of aryl chlorides.

see article for more examples

see article for more reactions

see article for more reactions

Triazole-Based Monophosphine Ligands for Palladium-Catalyzed Cross-Coupling Reactions of Aryl Chlorides

Q. Dai, W. Gao, D. Liu, L. M. Kapes, X. Zhang, J. Org. Chem., 2006, 71, 3928-3934.

Key Words

1,2,3-Triazoles, Phosphines, Suzuki Coupling, Buchwald-Hartwig Coupling, Biaryl Synthesis, Aryl Amines

ID: J54-Y2005-1780