Rapid and Solvent-Free Synthesis of Homoallyl or Homopropargyl Alcohols Mediated by Zinc Powder
Jin-xian Wang*, Xuefeng Jia, Tuanjie Meng, Li Xin
*Institute of Chemistry, Department of Chemistry, Northwest Normal University, 967 An Ning Road (E.), Lanzhou 730070, P. R. China, Email: wangjxnwnu.edu.cn
J.-X. Wang, X. Jia, T. Meng, L. Xin, Synthesis, 2005, 2669-2672.
see article for more reactions
A rapid and efficient procedure for the solvent-free synthesis of homoallylic and homopropargyl alcohols has been achieved by zinc-mediated Barbier-type reaction of carbonyl compounds at room temperature.
see article for more examples
J.-X. Wang, Y. Fu, Y. Hu, K. Wang, Synthesis, 2003, 1506-1510.