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Simple, Efficient, and Selective Deprotection of Phenolic Methoxymethyl Ethers Using Silica-Supported Sodium Hydrogen Sulfate as a Heterogeneous Catalyst

C. Ramesh, N. Ravindranath and Biswanath Das*

*Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India, Email: biswanathdasyahoo.com

C. Ramesh, N. Ravindranath, B. Das, J. Org. Chem., 2003, 68, 7101-7103.

DOI: 10.1021/jo030088+ (free Supporting Information)


Abstract

A simple and efficient method has been developed for chemoselective deprotection of phenolic methoxymethyl (MOM) ethers at room temperature using silica-supported sodium hydrogen sulfate as a heterogeneous catalyst.

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Key Words

MOM Ethers, Deprotection (Acetals)


ID: J42-Y2003-1250