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Reductive One-Carbon Homologation of Aldehydes and Ketones

Hélène Lebel* and Chehla Ladjel

*Département de chimie, Université de Montréal, P.O. Box 6128, Station Downtown, Montréal, Québec, Canada H3C 3J7, Email:

H. Lebel, C. Ladjel, J. Org. Chem., 2005, 70, 10159-10161.

DOI: 10.1021/jo0516741

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A rhodium-catalyzed methylenation-hydrogenation cascade process allows the homologation of carbonyl compounds to alkanes in high yields.

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Rhodium-Catalyzed Methylenation of Aldehydes

H. Lebel, V. Paquet, J. Am. Chem. Soc., 2004, 126, 320-328.

Key Words

Methylenation, Triphenylphosphine, Hydrogen

ID: J42-Y2005-2020