Organic Chemistry Portal

Abstracts

Search:

Regioselective Heck Couplings of α,β-Unsaturated Tosylates and Mesylates with Electron-Rich Olefins

Anders Lindhardt Hansen and Troels Skrydstrup*

*Department of Chemistry and the Interdisciplinary Nanoscience Center, University of Aarhus, Langelandsgade 140, 8000 Aarhus C, Denmark, Email: tschem.au.dk

A. L. Hansen, T. Skrydstrup, Org. Lett., 2005, 7, 5585-5587.

DOI: 10.1021/ol052136d (free Supporting Information)


see article for more reactions

Abstract

Highly regioselective Heck couplings of α,β-unsaturated tosylate and mesylate derivatives with N-acyl N-vinylamines and vinyl ethers were achieved. This method provides a cheap alternative to similar couplings using a triflate electrophile.

see article for more examples



Key Words

Heck Reaction, Unsaturated Compounds, Dienes


ID: J54-Y2005-2040